• Concomitant Temperature Stress and Immune Activation may Increase Mortality Despite Efficient Clearance of an Intracellular Bacterial Infection in Atlantic Cod 

      Larsen, Anett Kristin; Nymo, Ingebjørg Helena; Sørensen, Karen Kristine; Seppola, Marit; Rødven, Rolf; Jiménez de Bagüés, María Pilar; Al Dahouk, Sascha; Godfroid, Jacques (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-04)
      The environmental temperature has profound effects on biological systems of marine aquatic organisms and plays a critical role in species distribution and abundance. Particularly during the warmer seasons, variations in habitat temperature may introduce episodes of stressful temperatures which the organisms must adapt to and compensate for to maintain physiological homeostasis. The marine environment ...
    • The quest for a true One Health perspective of brucellosis 

      Godfroid, Jacques; De Bolle, Xavier; Roop, R. Martin I.I.; O'Callaghan, David; Tsolis, Renée M.; Baldwin, Cynthia L.; Santos, Renato L.; McGiven, John A.; Olsen, Steven C.; Nymo, Ingebjørg Helena; Larsen, Anett Kristin; Al Dahouk, Sascha; Letesson, Jean-Jacques (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Shedding of Brucella melitensis happens through milk macrophages in the murine model of infection 

      Jansen, Wiebke; Demars, Aurore; Nicaise, Charles; Godfroid, Jacques; Xavier, de Bolle; Reboul, Angeline; Al Dahouk, Sascha (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-10)
      Although shedding of zoonotic brucellae in milk has been demonstrated in natural hosts, these data are still missing for the standard murine infection model. We therefore analysed shedding kinetics and the niche of <i>B. melitensis</i> in murine milk. Pregnant Balb/cByJ mice were intraperitoneally infected with 10<sup>5</sup> CFU of the 16 M reference strain, a 16 M mCherry mutant or a human isolate. ...